Animus

"Animus" was Anna Ripley's pepperbox pistol, her second designed gun. This gun was a vast improvement from Ripley's first design, Retort, as it had six barrels, unlike the Retort which only had four. Not only were there more barrels, but also one of the barrels was magically enchanted. A bullet fired from this barrel dealt additional psychic damage to the target. When Animus jammed, it dealt 2d6 psychic damage to the wielder.

The gun was similar in design to Percy's pepperbox pistol "The List". However, it was thinner, longer, and more refined. The gun was a deep gunmetal grey color with brass sections. It also had some whitestone built into it.

The demon of vengeance, Orthax, was bound to Ripley through Animus, much like he was to Percy through his pepperbox pistol "The List". The names of the people that Ripley sought vengeance against were inscribed on each of the barrels of Animus, just like on Percy's "The List". When Vox Machina encountered Ripley on Glintshore in, two of the barrels were already blank, with no names on them. The other four barrels had the following names on them:
 * Percival de Rolo
 * Oz Grud
 * King Bertrand Dwendell
 * Richter Wells

After Ripley dealt the finishing blow on Percy, his name vanished from the barrel in a puff of black smoke.

When Keyleth severed Orthax's connection to Animus via her Greater Restoration spell, the remaining names on the barrels vanished in a flash of shadow. However, when Percy later attuned Animus to himself, the names were still on the gun and vanished again with a dark glow. It's possible this was an error made by Matthew Mercer.