Mage's Disjunction

Mage's Disjunction is a powerful spell that removes all magical effects in a wide area, and can disenchant magic items.

Description
Mage's Disjunction requires one action to cast, verbal components. The spell creates a 40-foot radius sphere in an area nearby to the caster that causes all magical effects and magic items to become disjoined. Doing so causes all spells and magical effects to end, and magical items that fail to resist the spell are stripped of their enchantments and become non-magical.

Artifacts are even able to be disjoined depending on the power of the caster, though successfully doing so has a chance to cause the caster to permanently lose the ability to cast any spell.

Additionally, sufficiently powerful casters have a chance when casting Mage's Disjunction to destroy an Antimagic Field.

History
A wizard from the Age of Arcanum, Laerryn Coramar-Seelie of Avalir, was aware of the spell and its limitations: no mortal spell could strip the magic from a solar's golden bow. The spell is known to leave residue.

Trivia

 * While Mage's Disjunction is not a spell in 5th Edition Dungeons & Dragons, it was a spell in 1st through 3rd editions, and is also known by the name Mordenkainen's Disjunction.
 * Because Mage's Disjunction is from an earlier edition of Dungeons & Dragons than is used on Critical Role, it is possible that this represents the knowledge to cast Mage's Disjunction having been lost after the Calamity.